Preferred Name

GTPase KRas

Synonyms
Definitions

GTPase KRas (189 aa, ~21 kDa) is encoded by the human KRAS gene. This protein is involved in the regulation of GTP metabolism and in signaling.

ID

http://purl.obolibrary.org/obo/NCIT_C17383

code

C17383

Contributing_Source

CTRP

definition

GTPase KRas (189 aa, ~21 kDa) is encoded by the human KRAS gene. This protein is involved in the regulation of GTP metabolism and in signaling.

DesignNote

There are at least 2 isoforms of GTPase KRas called K-Ras4A and K-Ras4B. These osoforms differ in the C-terminal region which is encoded by two alternative exons (IVA and IVB). UniProt considers K-Ras4A the canonical isoform.

Display_Name

GTPase KRas

in_subset

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C142800

http://purl.obolibrary.org/obo/NCIT_C142799

label

GTPase KRas

Legacy Concept Name

p21_K-Ras_Protein

OMIM_Number

190070

Preferred_Name

GTPase KRas

prefixIRI

NCIT:C17383

prefLabel

GTPase KRas

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

Swiss_Prot

P01116

UMLS_CUI

C0763464

subClassOf

http://purl.obolibrary.org/obo/NCIT_C17388

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