loading...| Preferred Name |
Tumor Suppressor Gene |
|
| Synonyms |
|
|
| Definitions |
Tumor Suppressor Genes encode proteins whose functions inhibit expression of tumorigenic phenotypes by holding cellular proliferation in check. When inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (NCI) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C17362 |
|
| ALT_DEFINITION |
A type of gene that makes a protein called a tumor suppressor protein that helps control cell growth. Mutations (changes in DNA) in antioncogenes may lead to cancer. |
|
| code |
C17362 |
|
| definition |
Tumor Suppressor Genes encode proteins whose functions inhibit expression of tumorigenic phenotypes by holding cellular proliferation in check. When inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (NCI) |
|
| Gene_Encodes_Product |
Tumor Suppressor Protein |
|
| label |
Tumor Suppressor Gene |
|
| Legacy Concept Name |
Tumor_Suppressor_Gene |
|
| Preferred_Name |
Tumor Suppressor Gene |
|
| prefixIRI |
NCIT:C17362 |
|
| prefLabel |
Tumor Suppressor Gene |
|
| Semantic_Type |
Gene or Genome |
|
| UMLS_CUI |
C0079427 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/CSP/1256-6400 | CRISP | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17362 | NCIT | LOOM | |
| http://purl.jp/bio/4/id/200906059615970213 | IOBC | LOOM | |
| http://www.projecthalo.com/aura#Tumor-Suppressor-Gene | AURA | LOOM | |
| http://sbmi.uth.tmc.edu/ontology/ochv#C0079427 | OCHV | LOOM |