Id http://purl.obolibrary.org/obo/NCIT_C173550
http://purl.obolibrary.org/obo/NCIT_C173550
Preferred Name

Hsp90 Inhibitor TQB3474

Definitions
An inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic activity. Upon administration, Hsp90 inhibitor TQB3474 specifically blocks Hsp90, which inhibits its chaperone function and promotes the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may lead to an inhibition of tumor cell proliferation. Hsp90, a chaperone complex protein upregulated in a variety of tumor cell types, regulates the folding and degradation of many oncogenic signaling proteins.
Type http://www.w3.org/2002/07/owl#Class
Delete Subject Author Type Created
No notes to display