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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C173442
http://purl.obolibrary.org/obo/NCIT_C173442
|
|---|---|
| Preferred Name | Autologous Monocyte-derived Lysate-pulsed Dendritic Cell Vaccine PV-001-DC |
| Definitions |
A cell-based cancer vaccine composed of autologous, monocyte-derived dendritic cells (mDCs) pulsed with tumor cell lysate containing tumor associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration,the autologous tumor cell lysate-pulsed mDCs vaccine PV-001-DC may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the patient's tumor cell-specific TAAs, which may result in tumor cell lysis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cell-based cancer vaccine composed of autologous, monocyte-derived dendritic cells (mDCs) pulsed with tumor cell lysate containing tumor associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration,the autologous tumor cell lysate-pulsed mDCs vaccine PV-001-DC may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the patient's tumor cell-specific TAAs, which may result in tumor cell lysis. |
|---|---|
| prefLabel | Autologous Monocyte-derived Lysate-pulsed Dendritic Cell Vaccine PV-001-DC
|
| label | Autologous Monocyte-derived Lysate-pulsed Dendritic Cell Vaccine PV-001-DC
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| NCI_META_CUI | CL1407425
|
| PDQ_Closed_Trial_Search_ID | 801794
|
| code | C173442
|
| prefixIRI | NCIT:C173442
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| in_subset | |
| Preferred_Name | Autologous Monocyte-derived Lysate-pulsed Dendritic Cell Vaccine PV-001-DC
|
| Maps_To | Autologous Monocyte-derived Lysate-pulsed Dendritic Cell Vaccine PV-001-DC
|
| NCI_Drug_Dictionary_ID | 801794
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 801794
|
| Semantic_Type |
Pharmacologic Substance
Cell
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