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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C173441
http://purl.obolibrary.org/obo/NCIT_C173441
|
|---|---|
| Preferred Name | Carbon C 14-pamiparib |
| Definitions |
An orally bioavailable radioconjugate composed of pamiparib, a nuclear enzyme poly(ADP-ribose) polymerase (PARP) inhibitor, radiolabeled with the radioisotope carbon C 14, with potential use for evaluating the pharmacokinetic profile of pamiparib. Pamiparib targets, binds to and inhibits PARP, which results in the inhibition of tumor cell proliferation and survival. Labeling of pamiparib with the radioactive tracer carbon C 14 allows for the evaluation of pamiparib's pharmacokinetic profile, including its absorption, distribution, metabolism and excretion (ADME).
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally bioavailable radioconjugate composed of pamiparib, a nuclear enzyme poly(ADP-ribose) polymerase (PARP) inhibitor, radiolabeled with the radioisotope carbon C 14, with potential use for evaluating the pharmacokinetic profile of pamiparib. Pamiparib targets, binds to and inhibits PARP, which results in the inhibition of tumor cell proliferation and survival. Labeling of pamiparib with the radioactive tracer carbon C 14 allows for the evaluation of pamiparib's pharmacokinetic profile, including its absorption, distribution, metabolism and excretion (ADME). |
|---|---|
| prefLabel | Carbon C 14-pamiparib
|
| label | Carbon C 14-pamiparib
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| NCI_META_CUI | CL1407424
|
| PDQ_Closed_Trial_Search_ID | 801792
|
| code | C173441
|
| prefixIRI | NCIT:C173441
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| in_subset | |
| Preferred_Name | Carbon C 14-pamiparib
|
| Maps_To | Carbon C 14-pamiparib
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| NCI_Drug_Dictionary_ID | 801792
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 801792
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| Semantic_Type |
Pharmacologic Substance
Indicator, Reagent, or Diagnostic Aid
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| Delete | Subject | Author | Type | Created |
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