loading...| Preferred Name |
Mast/Stem Cell Growth Factor Receptor Kit |
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| Synonyms |
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| Definitions |
Mast/stem cell growth factor receptor Kit (976 aa, ~110 kDa) is encoded by the human KIT gene. This protein is involved in cell survival, tyrosine phosphorylation and ligand-mediated signaling. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17328 |
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| ALT_DEFINITION |
A protein on the surface of some cells that binds to biologic substance called stem cell factor (SCF). SCF causes certain types of blood cells to grow. The stem cell factor receptor is found at high levels or in a changed form on some types of cancer cells. This may cause these cells to grow rapidly when SCF is present. The stem cell factor receptor is a type of receptor tyrosine kinase. |
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| code |
C17328 |
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| Contributing_Source |
CPTAC CTRP GDC |
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| definition |
Mast/stem cell growth factor receptor Kit (976 aa, ~110 kDa) is encoded by the human KIT gene. This protein is involved in cell survival, tyrosine phosphorylation and ligand-mediated signaling. |
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| Display_Name |
Mast/Stem Cell Growth Factor Receptor Kit |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C156952 http://purl.obolibrary.org/obo/NCIT_C156953 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C159414 http://purl.obolibrary.org/obo/NCIT_C157711 |
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| Is_Value_For_GDC_Property | ||
| label |
Mast/Stem Cell Growth Factor Receptor Kit |
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| Legacy Concept Name |
Stem_Cell_Factor_Receptor |
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| Maps_To |
CD117 |
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| OMIM_Number |
164920 |
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| Preferred_Name |
Mast/Stem Cell Growth Factor Receptor Kit |
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| prefixIRI |
NCIT:C17328 |
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| prefLabel |
Mast/Stem Cell Growth Factor Receptor Kit |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
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| Swiss_Prot |
P10721 |
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| UMLS_CUI |
C0072470 |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/SNOMEDCT/103165007 | SNOMEDCT | LOOM | |
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C17328 | NCIT | LOOM | |
| http://www.drugtargetontology.org/dto/DTO_03100231 | DTO | LOOM |