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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17319
http://purl.obolibrary.org/obo/NCIT_C17319
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|---|---|
| Preferred Name | Receptor Tyrosine-Protein Kinase erbB-2 |
| Definitions |
Receptor tyrosine-protein kinase erbB-2 (1255 aa, ~138 kDa) is encoded by the human ERBB2 gene. This protein is involved in cell proliferation, tyrosine phosphorylation and signal transduction.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Receptor tyrosine-protein kinase erbB-2 (1255 aa, ~138 kDa) is encoded by the human ERBB2 gene. This protein is involved in cell proliferation, tyrosine phosphorylation and signal transduction. |
|---|---|
| prefLabel | Receptor Tyrosine-Protein Kinase erbB-2
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| label | Receptor Tyrosine-Protein Kinase erbB-2
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| code | C17319
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| prefixIRI | NCIT:C17319
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| OMIM_Number | 164870
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| in_subset | |
| Display_Name | Receptor Tyrosine-Protein Kinase erbB-2
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| Preferred_Name | Receptor Tyrosine-Protein Kinase erbB-2
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| Contributing_Source | CTRP
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| Swiss_Prot | P04626
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| Legacy Concept Name | ERBB2_Receptor_Protein-Tyrosine_Kinase
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| DesignNote | Receptor tyrosine-protein kinase erbB-2 is a ligandless receptor and only has activity after dimerization with other ErbB receptors.
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| type | |
| ALT_DEFINITION | A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer cells removed from the body may be tested for the presence of c-erbB-2 to help decide the best type of treatment. c-erbB-2 is a type of receptor tyrosine kinase.
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| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
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| UMLS_CUI | C1702024
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