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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C172924
http://purl.obolibrary.org/obo/NCIT_C172924
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|---|---|
| Preferred Name | Anti-Ribonucleoprotein Antibody ATRC-101 |
| Definitions |
An engineered, human immunoglobulin (Ig) G1 monoclonal antibody directed against a ribonucleoprotein (RNP) complex, with potential immunostimulating and antineoplastic activities. Upon administration, anti-RNP antibody ATRC-101 targets and binds to its RNP complex antigen on tumor cells. This may activate the innate immune system, change the local tumor microenvironment (TME) and promote T cell-mediated killing of tumor cells. The tumor-restricted RNP complex is expressed in a variety of tumor cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An engineered, human immunoglobulin (Ig) G1 monoclonal antibody directed against a ribonucleoprotein (RNP) complex, with potential immunostimulating and antineoplastic activities. Upon administration, anti-RNP antibody ATRC-101 targets and binds to its RNP complex antigen on tumor cells. This may activate the innate immune system, change the local tumor microenvironment (TME) and promote T cell-mediated killing of tumor cells. The tumor-restricted RNP complex is expressed in a variety of tumor cells. |
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| label | Anti-Ribonucleoprotein Antibody ATRC-101
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| prefLabel | Anti-Ribonucleoprotein Antibody ATRC-101
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| in_subset |
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| Preferred_Name | Anti-Ribonucleoprotein Antibody ATRC-101
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| Is_Value_For_GDC_Property | |
| Display_Name | Anti-Ribonucleoprotein Antibody ATRC-101
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| Maps_To | Anti-Ribonucleoprotein Antibody ATRC-101
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| PDQ_Open_Trial_Search_ID | 802038
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| prefixIRI | NCIT:C172924
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| NCI_Drug_Dictionary_ID | 802038
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| Contributing_Source | CTRP
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| subClassOf | |
| code | C172924
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| type | |
| PDQ_Closed_Trial_Search_ID | 802038
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| Semantic_Type | Pharmacologic Substance
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| NCI_META_CUI | CL1406946
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