loading...| Preferred Name |
D(2) Dopamine Receptor |
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| Synonyms |
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| Definitions |
D(2) dopamine receptor (443 aa, ~51 kDa) is encoded by the human DRD2 gene. This protein plays a role in dopamine binding, angiogenesis inhibition, and receptor signaling. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17292 |
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| code |
C17292 |
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| Contributing_Source |
CTRP |
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| definition |
D(2) dopamine receptor (443 aa, ~51 kDa) is encoded by the human DRD2 gene. This protein plays a role in dopamine binding, angiogenesis inhibition, and receptor signaling. |
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| DesignNote |
Neurotransmission mediated by the Dopamine D2 Receptor (DRD2) plays a key role in the control of movement, in reward and reinforcement mechanisms in psychiatric disorders, and in the neuromodulation of appetitive behaviors. Acting through D2 dopamine receptors, dopamine specifically inhibits the vascular permeabilizing and angiogenic activities of VEGF by inducing endocytosis of VEGF receptor 2, preventing VEGF binding, receptor phosphorylation, and signaling. (OMIM) |
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| Display_Name |
D(2) Dopamine Receptor |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
D(2) Dopamine Receptor |
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| Legacy Concept Name |
Dopamine_Receptor-D2 |
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| OMIM_Number |
126450 |
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| Preferred_Name |
D(2) Dopamine Receptor |
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| prefixIRI |
NCIT:C17292 |
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| prefLabel |
D(2) Dopamine Receptor |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Receptor |
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| Swiss_Prot |
P14416 |
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| UMLS_CUI |
C3659270 |
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| subClassOf |