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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17290
http://purl.obolibrary.org/obo/NCIT_C17290
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|---|---|
| Preferred Name | Dihydropyrimidine Dehydrogenase [NADP(+)] |
| Definitions |
Dihydropyrimidine dehydrogenase [NADP(+)] (1025 aa, ~111 kDa) is encoded by the human DPYD gene. This protein is involved in the degradation of pyrimidines.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Dihydropyrimidine dehydrogenase [NADP(+)] (1025 aa, ~111 kDa) is encoded by the human DPYD gene. This protein is involved in the degradation of pyrimidines. |
|---|---|
| prefLabel | Dihydropyrimidine Dehydrogenase [NADP(+)]
|
| label | Dihydropyrimidine Dehydrogenase [NADP(+)]
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| code | C17290
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| prefixIRI | NCIT:C17290
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| OMIM_Number | 612779
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| in_subset | |
| Display_Name | Dihydropyrimidine Dehydrogenase [NADP(+)]
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| Preferred_Name | Dihydropyrimidine Dehydrogenase [NADP(+)]
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| Contributing_Source | CTRP
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| Swiss_Prot | Q12882
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| Legacy Concept Name | Dihydropyrimidine_Dehydrogenase
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| DesignNote | Dihydropyrimidine dehydrogenase [NADP(+)] can catabolize fluorouracil-based chemotherapy drugs. Therefore the expression and activity levels of this enzyme affect therapeutic efficacy and toxicity in patients receiving this type of chemotherapy.
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C0058126
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