Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C172809
http://purl.obolibrary.org/obo/NCIT_C172809
|
|---|---|
| Preferred Name | Tyrosine Kinase Inhibitor TL-895 |
| Definitions |
An orally bioavailable inhibitor of tyrosine kinase, with potential anti-inflammatory and antineoplastic activities. Upon oral administration, tyrosine kinase inhibitor TL-895 targets, binds to, and inhibits tyrosine kinase. This may result in the inhibition of tumor angiogenesis and cell proliferation, and the inhibition of immune-mediated inflammatory processes. Tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. In addition, they play important roles in the activation of leukocytes and in many immune-mediated inflammatory and autoimmune conditions.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally bioavailable inhibitor of tyrosine kinase, with potential anti-inflammatory and antineoplastic activities. Upon oral administration, tyrosine kinase inhibitor TL-895 targets, binds to, and inhibits tyrosine kinase. This may result in the inhibition of tumor angiogenesis and cell proliferation, and the inhibition of immune-mediated inflammatory processes. Tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation and metastasis. In addition, they play important roles in the activation of leukocytes and in many immune-mediated inflammatory and autoimmune conditions. |
|---|---|
| prefLabel | Tyrosine Kinase Inhibitor TL-895
|
| label | Tyrosine Kinase Inhibitor TL-895
|
| NCI_META_CUI | CL1406868
|
| PDQ_Closed_Trial_Search_ID | 801850
|
| code | C172809
|
| prefixIRI | NCIT:C172809
|
| in_subset |
See more
See less
|
| Display_Name | Tyrosine Kinase Inhibitor TL-895
|
| Preferred_Name | Tyrosine Kinase Inhibitor TL-895
|
| Contributing_Source | CTRP
|
| Maps_To | Tyrosine Kinase Inhibitor TL-895
|
| NCI_Drug_Dictionary_ID | 801850
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 801850
|
| Semantic_Type | Pharmacologic Substance
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |