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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1728
http://purl.obolibrary.org/obo/NCIT_C1728
|
|---|---|
| Preferred Name | Celecoxib |
| Definitions |
A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis. |
|---|---|
| label | Celecoxib
|
| prefLabel | Celecoxib
|
| Legacy Concept Name | Celecoxib
|
| in_subset |
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| Preferred_Name | Celecoxib
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| Is_Value_For_GDC_Property | |
| Chemical_Formula | C17H14F3N3O2S
|
| Display_Name | Celecoxib
|
| Maps_To | Celecoxib
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| PDQ_Open_Trial_Search_ID | 43023
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| Has_Target | |
| UMLS_CUI | C0538927
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| FDA_UNII_Code | JCX84Q7J1L
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| prefixIRI | NCIT:C1728
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| Accepted_Therapeutic_Use_For | Acute pain; Familial adenomatous polyposis; Primary dysmenorrhea; Osteoarthritis; Rheumatoid arthritis
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| NCI_Drug_Dictionary_ID | 43023
|
| Contributing_Source |
CTRP
FDA
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| subClassOf | |
| CHEBI_ID | CHEBI:41423
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| code | C1728
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| type | |
| ALT_DEFINITION | A drug that reduces pain. Celecoxib belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is being studied in the prevention of cancer.
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| NSC Number | 719627
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| PDQ_Closed_Trial_Search_ID | 43023
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| CAS_Registry | 169590-42-5
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