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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17270
http://purl.obolibrary.org/obo/NCIT_C17270
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|---|---|
| Preferred Name | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase |
| Definitions |
An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. (from LocusLink)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. (from LocusLink) |
|---|---|
| prefLabel | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase
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| label | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase
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| code | C17270
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| prefixIRI | NCIT:C17270
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| in_subset | |
| Display_Name | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase
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| Preferred_Name | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase
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| Contributing_Source | CTRP
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| Legacy Concept Name | Phosphatidylinositol-3_Kinase
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| type | |
| ALT_DEFINITION | A type of enzyme that transmits signals in cells and that helps control cell growth. Some tumors have higher-than-normal levels of phosphatidylinositol-3 kinase.
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| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C0044602
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