Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
Jump to:
| Id | http://purl.obolibrary.org/obo/NCIT_C17242
http://purl.obolibrary.org/obo/NCIT_C17242
|
|---|---|
| Preferred Name | Urokinase-Type Plasminogen Activator |
| Definitions |
Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor binding and the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor binding and the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin. |
|---|---|
| label |
Urokinase-Type Plasminogen Activator
|
| prefLabel |
Urokinase-Type Plasminogen Activator
|
| Legacy Concept Name |
Urokinase
|
| in_subset | |
| Preferred_Name |
Urokinase-Type Plasminogen Activator
|
| Display_Name |
Urokinase-Type Plasminogen Activator
|
| Swiss_Prot |
P00749
|
| DesignNote |
Urokinase-type plasminogen activator is found in high and low molecular mass forms. Each form is comprised of two chains, A and B. The high molecular mass form contains a long chain A which is cleaved to yield a short chain A. (UniProt)
|
| prefixIRI |
NCIT:C17242
|
| Contributing_Source |
CTRP
|
| subClassOf | |
| code |
C17242
|
| type | |
| ALT_DEFINITION |
An enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory and used to dissolve blood clots or to prevent them from forming.
|
| OMIM_Number |
191840
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
|
| NCI_META_CUI |
CL790344
|
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |