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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C172058
http://purl.obolibrary.org/obo/NCIT_C172058
|
|---|---|
| Preferred Name | Cord Blood Derived CAR T-Cells |
| Definitions |
A preparation of umbilical cord blood (CB)-derived T-lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) that targets an as of yet unidentified tumor-associated antigen (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration of the cord blood derived CAR T-cells, the T-cells target, bind to and induce selective cytotoxicity in tumor cells expressing the TAA.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A preparation of umbilical cord blood (CB)-derived T-lymphocytes that are genetically engineered to express a chimeric antigen receptor (CAR) that targets an as of yet unidentified tumor-associated antigen (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration of the cord blood derived CAR T-cells, the T-cells target, bind to and induce selective cytotoxicity in tumor cells expressing the TAA. |
|---|---|
| prefLabel | Cord Blood Derived CAR T-Cells
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| label | Cord Blood Derived CAR T-Cells
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| NCI_META_CUI | CL1406190
|
| PDQ_Closed_Trial_Search_ID | 801490
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| code | C172058
|
| prefixIRI | NCIT:C172058
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| in_subset | |
| Preferred_Name | Cord Blood Derived CAR T-Cells
|
| Maps_To | Cord Blood Derived CAR T-Cells
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| NCI_Drug_Dictionary_ID | 801490
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 801490
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| Semantic_Type | Pharmacologic Substance
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