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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C171392
http://purl.obolibrary.org/obo/NCIT_C171392
|
|---|---|
| Preferred Name | Individualized MVA-based Vaccine TG4050 |
| Definitions |
An off-the-shelf (OTS) individualized vaccine comprised of a modified Vaccinia virus Ankara (MVA) viral vector encoding tumor-specific neoantigens (TSNAs), with potential immunostimulatory and antineoplastic activities. Following administration of the individualized MVA-based vaccine TG4050, the neoantigens are expressed and presented to the immune system, which induces the activation of a specific cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing the patient-specific neoantigens.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An off-the-shelf (OTS) individualized vaccine comprised of a modified Vaccinia virus Ankara (MVA) viral vector encoding tumor-specific neoantigens (TSNAs), with potential immunostimulatory and antineoplastic activities. Following administration of the individualized MVA-based vaccine TG4050, the neoantigens are expressed and presented to the immune system, which induces the activation of a specific cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing the patient-specific neoantigens. |
|---|---|
| prefLabel | Individualized MVA-based Vaccine TG4050
|
| label | Individualized MVA-based Vaccine TG4050
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| NCI_META_CUI | CL1405501
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| PDQ_Closed_Trial_Search_ID | 801297
|
| code | C171392
|
| prefixIRI | NCIT:C171392
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| in_subset | |
| Display_Name | Individualized MVA-based Vaccine TG4050
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| Preferred_Name | Individualized MVA-based Vaccine TG4050
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| Contributing_Source | CTRP
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| Maps_To | Individualized MVA-based Vaccine TG4050
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| NCI_Drug_Dictionary_ID | 801297
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 801297
|
| Semantic_Type | Pharmacologic Substance
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