An injectable formulation composed of the two Chinese medicinal herbs Radix astragali, the root of astragalus membranaceus (huangqi) and Radix codonopsis, the root of Codonopsis pilosula (dangshen), with potential antineoplastic adjuvant and chemoprotective activities that may prevent cancer-related fatigue. Although the exact mechanisms by which shenqi fuzheng injection (SFI) have yet to be fully elucidated, the herbs may improve tumor response and/or reduce the toxicity of certain chemotherapeutics when administered together. It may also alleviate chemotherapy-associated immunosuppression.