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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17073
http://purl.obolibrary.org/obo/NCIT_C17073
|
|---|---|
| Preferred Name | Interleukin-2 Receptor Subunit Alpha |
| Definitions |
Interleukin-2 receptor subunit alpha (272 aa, ~31 kDa) is encoded by the human IL2RA gene. This protein plays a role in interleukin-2-dependent signaling.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Interleukin-2 receptor subunit alpha (272 aa, ~31 kDa) is encoded by the human IL2RA gene. This protein plays a role in interleukin-2-dependent signaling. |
|---|---|
| prefLabel | Interleukin-2 Receptor Subunit Alpha
|
| label | Interleukin-2 Receptor Subunit Alpha
|
| code | C17073
|
| prefixIRI | NCIT:C17073
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| OMIM_Number | 147730
|
| in_subset | |
| Display_Name | Interleukin-2 Receptor Subunit Alpha
|
| Preferred_Name | Interleukin-2 Receptor Subunit Alpha
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| Contributing_Source |
CTRP
GDC
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| Swiss_Prot | P01589
|
| Maps_To | CD25
|
| Legacy Concept Name | Interleukin-2_Receptor_Alpha
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| DesignNote | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. (LocusLink)
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
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| UMLS_CUI | C1700887
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| Delete | Subject | Author | Type | Created |
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