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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17061
http://purl.obolibrary.org/obo/NCIT_C17061
|
|---|---|
| Preferred Name | RAS Family Oncogene |
| Definitions |
A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten murine sarcoma viruses. Mutated or overexpressed forms of the human ras genes are associated with constitutive ras GTPase activity, increased cellular proliferation, and cell transformation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten murine sarcoma viruses. Mutated or overexpressed forms of the human ras genes are associated with constitutive ras GTPase activity, increased cellular proliferation, and cell transformation. |
|---|---|
| prefLabel | RAS Family Oncogene
|
| label | RAS Family Oncogene
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| code | C17061
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| prefixIRI | NCIT:C17061
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| in_subset | |
| Display_Name | RAS Family Oncogene
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| Preferred_Name | RAS Family Oncogene
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| Contributing_Source | CTRP
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| Legacy Concept Name | RAS_Family_Oncogene
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| type | |
| subClassOf | |
| Semantic_Type | Gene or Genome
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| UMLS_CUI | C0034678
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