Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Ipratropium Bromide Anhydrous
Synonyms
Definitions

The bromide salt form of anhydrous ipratropium, a synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic, postganglionic, effector-cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation.
ID

http://purl.obolibrary.org/obo/NCIT_C170538
CAS_Registry

22254-24-6
Chemical_Formula

C20H30NO3.Br
code

C170538
Contributing_Source

FDA
definition

The bromide salt form of anhydrous ipratropium, a synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic, postganglionic, effector-cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation.
FDA_UNII_Code

VJV4X1P2Z1
Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C61794
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Ipratropium Bromide Anhydrous
Legacy Concept Name

Ipratropium_Bromide
NCI_META_CUI

CL1382973
Preferred_Name

Ipratropium Bromide Anhydrous
prefixIRI

NCIT:C170538
prefLabel

Ipratropium Bromide Anhydrous
Semantic_Type

Pharmacologic Substance
subClassOf

http://purl.obolibrary.org/obo/NCIT_C319

http://purl.obolibrary.org/obo/NCIT_C29704
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