Preferred Name

Protein Tyrosine Kinase

Synonyms
Definitions

Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online)

ID

http://purl.obolibrary.org/obo/NCIT_C17020

code

C17020

definition

Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online)

DesignNote

Formerly 2.7.1.112

label

Protein Tyrosine Kinase

Legacy Concept Name

Protein_Tyrosine_Kinase

Preferred_Name

Protein Tyrosine Kinase

prefixIRI

NCIT:C17020

prefLabel

Protein Tyrosine Kinase

Semantic_Type

Amino Acid, Peptide, or Protein

Enzyme

UMLS_CUI

C0033681

subClassOf

http://purl.obolibrary.org/obo/NCIT_C17018

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