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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C16743
http://purl.obolibrary.org/obo/NCIT_C16743
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|---|---|
| Preferred Name | Insulin-Like Growth Factor I |
| Definitions |
Insulin-like growth factor I (195 aa, ~22 kDa) is encoded by the human IGF1 gene. This protein may be involved in the regulation of glucose metabolism.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Insulin-like growth factor I (195 aa, ~22 kDa) is encoded by the human IGF1 gene. This protein may be involved in the regulation of glucose metabolism. |
|---|---|
| prefLabel | Insulin-Like Growth Factor I
|
| label | Insulin-Like Growth Factor I
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| code | C16743
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| prefixIRI | NCIT:C16743
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| OMIM_Number | 147440
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| in_subset | |
| Display_Name | Insulin-Like Growth Factor I
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| Preferred_Name | Insulin-Like Growth Factor I
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| Contributing_Source | CTRP
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| Swiss_Prot | P05019
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| Legacy Concept Name | Insulin-Like_Growth_Factor-1
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| DesignNote | Elevated serum levels of insulin-like growth factor-1 (IGF-1) may identify premenopausal women who are likely to develop breast cancer before age 50. (Int J Cancer. 2000; 88: 828-832, via Medscape)
Similar to insulin, the full length insulin-like growth factor I precursor protein is cleaved at positions 48 and 188 to release a 70 amino acid growth factor and a 77 amino acid E peptide. (UniProt)
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C3712803
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