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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C167360
http://purl.obolibrary.org/obo/NCIT_C167360
|
|---|---|
| Preferred Name | Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918 |
| Definitions |
A prime cancer vaccine comprised of a genetically engineered, replication-deficient adenovirus serotype 26 (Ad26) encoding the oncogenic human papillomavirus 16 (HPV16), with potential immunostimulating and antineoplastic activities. Upon intramuscular administration of Ad26-expressing HPV16 vaccine JNJ-63682918, the adenovirus infects and expresses HPV16. The expressed proteins stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 antigens, thereby inducing tumor cell lysis. HPV16 infection plays a key role in the development of a variety of cancers.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A prime cancer vaccine comprised of a genetically engineered, replication-deficient adenovirus serotype 26 (Ad26) encoding the oncogenic human papillomavirus 16 (HPV16), with potential immunostimulating and antineoplastic activities. Upon intramuscular administration of Ad26-expressing HPV16 vaccine JNJ-63682918, the adenovirus infects and expresses HPV16. The expressed proteins stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 antigens, thereby inducing tumor cell lysis. HPV16 infection plays a key role in the development of a variety of cancers. |
|---|---|
| prefLabel | Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918
|
| label | Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918
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| NCI_META_CUI | CL972334
|
| code | C167360
|
| Has_Target | |
| prefixIRI | NCIT:C167360
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| in_subset | |
| Display_Name | Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918
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| Preferred_Name | Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918
|
| Contributing_Source | CTRP
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| Maps_To | Adenovirus Serotype 26-expressing HPV16 Vaccine JNJ-63682918
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Pharmacologic Substance
Immunologic Factor
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