Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1670
http://purl.obolibrary.org/obo/NCIT_C1670
|
|---|---|
| Preferred Name | Ibandronate Sodium |
| Definitions |
The sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain. |
|---|---|
| prefLabel | Ibandronate Sodium
|
| label | Ibandronate Sodium
|
| PDQ_Closed_Trial_Search_ID | 365963
|
| code | C1670
|
| prefixIRI | NCIT:C1670
|
| in_subset |
See more
See less
|
| Display_Name | Ibandronate Sodium
|
| Preferred_Name | Ibandronate Sodium
|
| FDA_UNII_Code | J12U072QL0
|
| Contributing_Source |
CTRP
FDA
|
| Chemical_Formula | C9H22NO7P2.Na.H2O
|
| Maps_To | Ibandronate Sodium
|
| CAS_Registry | 138926-19-9
|
| NCI_Drug_Dictionary_ID | 365963
|
| Legacy Concept Name | Ibandronate
|
| type | |
| ALT_DEFINITION | A drug that is used to prevent and treat osteoporosis, and is being studied in the treatment of cancer that has spread to the bones. It belongs to the family of drugs called bisphosphonates.
|
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 365963
|
| Accepted_Therapeutic_Use_For | Osteoporosis, treatment and prevention
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0772244
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |