Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C164211
http://purl.obolibrary.org/obo/NCIT_C164211
|
|---|---|
| Preferred Name | Multi-mode Kinase Inhibitor EOC317 |
| Definitions |
An orally available, small molecule, multi-mode kinase inhibitor (MMKI), with potential antineoplastic activity. Upon oral administration, MMKI EOC317 targets, binds to and inhibits the activity of a variety of kinases, such as phosphatidylinositol 3 kinase (PI3K), and the receptor tyrosine kinases, fibroblast growth factor receptor (FGFR), angiopoietin-1 receptor (TIE 2), and vascular endothelial growth factor receptor-2 (VEGFR-2). This inhibition may result in an induction of apoptosis of susceptible tumors cells in which these kinases are overexpressed.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An orally available, small molecule, multi-mode kinase inhibitor (MMKI), with potential antineoplastic activity. Upon oral administration, MMKI EOC317 targets, binds to and inhibits the activity of a variety of kinases, such as phosphatidylinositol 3 kinase (PI3K), and the receptor tyrosine kinases, fibroblast growth factor receptor (FGFR), angiopoietin-1 receptor (TIE 2), and vascular endothelial growth factor receptor-2 (VEGFR-2). This inhibition may result in an induction of apoptosis of susceptible tumors cells in which these kinases are overexpressed. |
|---|---|
| prefLabel | Multi-mode Kinase Inhibitor EOC317
|
| label | Multi-mode Kinase Inhibitor EOC317
|
| NCI_META_CUI | CL977499
|
| PDQ_Closed_Trial_Search_ID | 799401
|
| code | C164211
|
| prefixIRI | NCIT:C164211
|
| in_subset | |
| Preferred_Name | Multi-mode Kinase Inhibitor EOC317
|
| FDA_UNII_Code | 44750KD9OE
|
| Contributing_Source | FDA
|
| Maps_To | Multi-mode Kinase Inhibitor EOC317
|
| CAS_Registry | 939805-30-8
|
| NCI_Drug_Dictionary_ID | 799401
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 799401
|
| Semantic_Type | Pharmacologic Substance
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |