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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C163994
http://purl.obolibrary.org/obo/NCIT_C163994
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|---|---|
| Preferred Name | Foslinanib Disodium |
| Definitions |
The disodium salt form of foslinanib, an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry activities. Upon oral administration, foslinanib targets and inhibits the formation of vasculogenic mimicry (VM; vascular mimicry). By destroying the VM channels and network, cancer cells are devoid of perfusion leading to an induction of cancer cell apoptosis and inhibition of cancer cell proliferation. VM is associated with tumor metastasis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The disodium salt form of foslinanib, an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry activities. Upon oral administration, foslinanib targets and inhibits the formation of vasculogenic mimicry (VM; vascular mimicry). By destroying the VM channels and network, cancer cells are devoid of perfusion leading to an induction of cancer cell apoptosis and inhibition of cancer cell proliferation. VM is associated with tumor metastasis. |
|---|---|
| prefLabel | Foslinanib Disodium
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| label | Foslinanib Disodium
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| NCI_META_CUI | CL977259
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| code | C163994
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| prefixIRI | NCIT:C163994
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| in_subset | |
| Preferred_Name | Foslinanib Disodium
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| FDA_UNII_Code | 8X5F5LAF7B
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| Contributing_Source | FDA
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| Maps_To | Foslinanib Disodium
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| CAS_Registry | 1256037-62-3
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type | Pharmacologic Substance
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