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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1634
http://purl.obolibrary.org/obo/NCIT_C1634
|
|---|---|
| Preferred Name | Cemadotin Hydrochloride |
| Definitions |
The hydrochloride salt form of cemadotin, a synthetic dolastatin 15 analogue with potential antineoplastic activity. Cemadotin suppresses spindle microtubule dynamics by binding to tubulin, thereby blocking mitosis. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The hydrochloride salt form of cemadotin, a synthetic dolastatin 15 analogue with potential antineoplastic activity. Cemadotin suppresses spindle microtubule dynamics by binding to tubulin, thereby blocking mitosis. (NCI04) |
|---|---|
| label | Cemadotin Hydrochloride
|
| prefLabel | Cemadotin Hydrochloride
|
| Has_Free_Acid_Or_Base_Form | |
| Legacy Concept Name | Cemadotin
|
| in_subset | |
| Preferred_Name | Cemadotin Hydrochloride
|
| Is_Value_For_GDC_Property | |
| DesignNote | CCR recorded NSC-D-669356
|
| Maps_To | Cemadotin Hydrochloride
|
| PDQ_Open_Trial_Search_ID | 42651
|
| UMLS_CUI | C0299746
|
| FDA_UNII_Code | 4LJQ1IXS6C
|
| prefixIRI | NCIT:C1634
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| NCI_Drug_Dictionary_ID | 42651
|
| Contributing_Source | FDA
|
| subClassOf | |
| code | C1634
|
| type | |
| ALT_DEFINITION | An anticancer drug that reduces the risk of tumor cell growth and reproduction.
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| NSC Number | D-669356
|
| PDQ_Closed_Trial_Search_ID | 42651
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| CAS_Registry | 172837-41-1
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| Delete | Subject | Author | Type | Created |
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| No notes to display |