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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C16325
http://purl.obolibrary.org/obo/NCIT_C16325
|
|---|---|
| Preferred Name | BCR/ABL1 Fusion Protein |
| Definitions |
A fusion protein encoded by the BCR/ABL1 fusion gene. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A fusion protein encoded by the BCR/ABL1 fusion gene. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein. |
|---|---|
| prefLabel | BCR/ABL1 Fusion Protein
|
| label | BCR/ABL1 Fusion Protein
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| code | C16325
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| prefixIRI | NCIT:C16325
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| in_subset | |
| Display_Name | BCR/ABL1 Fusion Protein
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| Preferred_Name | BCR/ABL1 Fusion Protein
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| Contributing_Source | CTRP
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| Legacy Concept Name | BCR-ABL_Oncoprotein
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| DesignNote | The BCR/ABL1 fusion protein is a constitutively activated tyrosine kinase and has a cytoplasmic localization, in contrast with the mostly nuclear localization of the tyrosine-protein kinase ABL1 protein. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
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| Related_To_Genetic_Biomarker | |
| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C0004891
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