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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C161599
http://purl.obolibrary.org/obo/NCIT_C161599
|
|---|---|
| Preferred Name | Antibody-drug Conjugate ABBV-011 |
| Definitions |
An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against an as of yet undisclosed tumor-associated antigen (TAA) linked to an undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of ABBV-011 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills tumor cells expressing this particular TAA through an as of yet undisclosed mechanism.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antibody-drug conjugate (ADC) composed of a monoclonal antibody directed against an as of yet undisclosed tumor-associated antigen (TAA) linked to an undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of ABBV-011 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills tumor cells expressing this particular TAA through an as of yet undisclosed mechanism. |
|---|---|
| prefLabel | Antibody-drug Conjugate ABBV-011
|
| label | Antibody-drug Conjugate ABBV-011
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| NCI_META_CUI | CL970130
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| PDQ_Closed_Trial_Search_ID | 798433
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| code | C161599
|
| prefixIRI | NCIT:C161599
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| in_subset |
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| Display_Name | Antibody-drug Conjugate ABBV-011
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| Preferred_Name | Antibody-drug Conjugate ABBV-011
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| Contributing_Source | CTRP
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| Maps_To | Antibody-drug Conjugate ABBV-011
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| NCI_Drug_Dictionary_ID | 798433
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 798433
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| Semantic_Type | Pharmacologic Substance
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