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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C160787
http://purl.obolibrary.org/obo/NCIT_C160787
|
|---|---|
| Preferred Name | Anti-CD52 Monoclonal Antibody ALLO-647 |
| Definitions |
A monoclonal antibody directed against the cell surface glycoprotein CD52 (CAMPATH-1 antigen; Cambridge pathology 1 antigen), with potential immunodepleting activity. Upon administration, anti-CD52 monoclonal antibody ALLO-647 selectively targets and binds to CD52, thereby triggering a host immune response that results in the lysis of CD52-positive lymphocytes. This leads to immunodepletion and may prevent graft-versus-host disease (GvHD). CD52 is a glycoprotein expressed on the surface of many immune cells, including essentially all B- and T-lymphocytes.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A monoclonal antibody directed against the cell surface glycoprotein CD52 (CAMPATH-1 antigen; Cambridge pathology 1 antigen), with potential immunodepleting activity. Upon administration, anti-CD52 monoclonal antibody ALLO-647 selectively targets and binds to CD52, thereby triggering a host immune response that results in the lysis of CD52-positive lymphocytes. This leads to immunodepletion and may prevent graft-versus-host disease (GvHD). CD52 is a glycoprotein expressed on the surface of many immune cells, including essentially all B- and T-lymphocytes. |
|---|---|
| prefLabel | Anti-CD52 Monoclonal Antibody ALLO-647
|
| label | Anti-CD52 Monoclonal Antibody ALLO-647
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| NCI_META_CUI | CL969759
|
| PDQ_Closed_Trial_Search_ID | 798418
|
| code | C160787
|
| Has_Target | |
| prefixIRI | NCIT:C160787
|
| in_subset |
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| Display_Name | Anti-CD52 Monoclonal Antibody ALLO-647
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| Preferred_Name | Anti-CD52 Monoclonal Antibody ALLO-647
|
| Contributing_Source | CTRP
|
| Maps_To | Anti-CD52 Monoclonal Antibody ALLO-647
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| NCI_Drug_Dictionary_ID | 798418
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 798418
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| Delete | Subject | Author | Type | Created |
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