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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1605
http://purl.obolibrary.org/obo/NCIT_C1605
|
|---|---|
| Preferred Name | Tecogalan Sodium |
| Definitions |
A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A sulfated polysaccharide isolated from various Arthrobacter bacterial species. Possessing potential antiangiogenic and antineoplastic properties, tecogalan binds to basic fibroblast growth factor (bFGF), thereby preventing bFGF from binding to its receptors. Disruption of this receptor binding results in the inhibition of bFGF-stimulated endothelial cell growth, proliferation, and migration. (NCI04) |
|---|---|
| prefLabel | Tecogalan Sodium
|
| label | Tecogalan Sodium
|
| PDQ_Closed_Trial_Search_ID | 42149
|
| code | C1605
|
| prefixIRI | NCIT:C1605
|
| in_subset | |
| Preferred_Name | Tecogalan Sodium
|
| Maps_To | Tecogalan Sodium
|
| NCI_Drug_Dictionary_ID | 42149
|
| Legacy Concept Name | Tecogalan_Sodium
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 42149
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0212199
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