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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1599
http://purl.obolibrary.org/obo/NCIT_C1599
|
|---|---|
| Preferred Name | Bicalutamide |
| Definitions |
A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. (NCI04) |
|---|---|
| prefLabel | Bicalutamide
|
| label | Bicalutamide
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| CHEBI_ID | CHEBI:3090
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| PDQ_Closed_Trial_Search_ID | 41298
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| code | C1599
|
| Has_Target | |
| prefixIRI | NCIT:C1599
|
| in_subset |
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| Display_Name | Bicalutamide
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| Preferred_Name | Bicalutamide
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| FDA_UNII_Code | A0Z3NAU9DP
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C18H14F4N2O4S
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| Maps_To | Bicalutamide
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| CAS_Registry | 90357-06-5
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| NSC Number | 722665
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| NCI_Drug_Dictionary_ID | 41298
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| Legacy Concept Name | Bicalutamide
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| type | |
| ALT_DEFINITION | An anticancer drug that belongs to the family of drugs called antiandrogens.
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| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 41298
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| Accepted_Therapeutic_Use_For | Metastatic prostate cancer
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0285590
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| Delete | Subject | Author | Type | Created |
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