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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C159892
http://purl.obolibrary.org/obo/NCIT_C159892
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|---|---|
| Preferred Name | CEA-targeting Agent RG6123 |
| Definitions |
An agent targeting the tumor-associated antigen (TAA) carcinoembryonic antigen (CEA), with potential antineoplastic activity. Upon administration, CEA-targeting agent RG6123 targets and binds to human CEA that is specifically expressed on certain tumor cells. This may, through an as of yet not elucidated mechanism of action, kill CEA-expressing tumor cells. CEA is overexpressed in many cancer cell types.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An agent targeting the tumor-associated antigen (TAA) carcinoembryonic antigen (CEA), with potential antineoplastic activity. Upon administration, CEA-targeting agent RG6123 targets and binds to human CEA that is specifically expressed on certain tumor cells. This may, through an as of yet not elucidated mechanism of action, kill CEA-expressing tumor cells. CEA is overexpressed in many cancer cell types. |
|---|---|
| label | CEA-targeting Agent RG6123
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| prefLabel | CEA-targeting Agent RG6123
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| in_subset |
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| Preferred_Name | CEA-targeting Agent RG6123
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| Is_Value_For_GDC_Property | |
| Display_Name | CEA-targeting Agent RG6123
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| Maps_To | CEA-targeting Agent RG6123
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| PDQ_Open_Trial_Search_ID | 797964
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| Has_Target | |
| prefixIRI | NCIT:C159892
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| NCI_Drug_Dictionary_ID | 797964
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| Contributing_Source | CTRP
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| subClassOf | |
| code | C159892
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| type | |
| PDQ_Closed_Trial_Search_ID | 797964
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| Semantic_Type | Pharmacologic Substance
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| NCI_META_CUI | CL968916
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