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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C159500
http://purl.obolibrary.org/obo/NCIT_C159500
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|---|---|
| Preferred Name | Taurultam Analogue GP-2250 |
| Definitions |
An oxathiazine-based structural analogue of taurultam (TRLT), which is the main derivative of the anti-infective agent taurolidine (TRD), with potential antineoplastic activity. Upon administration, GP-2250 selectively induces reactive oxygen species (ROS)-mediated apoptosis in and inhibits proliferation of susceptible tumor cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An oxathiazine-based structural analogue of taurultam (TRLT), which is the main derivative of the anti-infective agent taurolidine (TRD), with potential antineoplastic activity. Upon administration, GP-2250 selectively induces reactive oxygen species (ROS)-mediated apoptosis in and inhibits proliferation of susceptible tumor cells. |
|---|---|
| prefLabel | Taurultam Analogue GP-2250
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| label | Taurultam Analogue GP-2250
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| NCI_META_CUI | CL951458
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| PDQ_Closed_Trial_Search_ID | 797809
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| code | C159500
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| prefixIRI | NCIT:C159500
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| in_subset |
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| Display_Name | Taurultam Analogue GP-2250
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| Preferred_Name | Taurultam Analogue GP-2250
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| Contributing_Source | CTRP
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| Maps_To | Taurultam Analogue GP-2250
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| NCI_Drug_Dictionary_ID | 797809
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 797809
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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