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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1590
http://purl.obolibrary.org/obo/NCIT_C1590
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|---|---|
| Preferred Name | Antineoplastic Alkylating Agent |
| Definitions |
An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth. |
|---|---|
| prefLabel | Antineoplastic Alkylating Agent
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| label | Antineoplastic Alkylating Agent
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| code | C1590
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| prefixIRI | NCIT:C1590
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| Preferred_Name | Antineoplastic Alkylating Agent
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| Legacy Concept Name | Antineoplastic_Alkylating_Agent
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C0282532
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