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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C156438
http://purl.obolibrary.org/obo/NCIT_C156438
|
|---|---|
| Preferred Name | Sibrotuzumab |
| Definitions |
A humanized monoclonal antibody (MoAb) against human fibroblast activation protein (FAP). FAP is a 95 kDa cell surface glycoprotein and an inducible tumor stromal antigen of epithelial cancers and of a subset of soft tissue sarcomas. FAP shows a very limited distribution pattern in normal tissues, thereby sibrotuzumab has possible diagnostic and therapeutic applications in epithelial cancers.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody (MoAb) against human fibroblast activation protein (FAP). FAP is a 95 kDa cell surface glycoprotein and an inducible tumor stromal antigen of epithelial cancers and of a subset of soft tissue sarcomas. FAP shows a very limited distribution pattern in normal tissues, thereby sibrotuzumab has possible diagnostic and therapeutic applications in epithelial cancers. |
|---|---|
| prefLabel | Sibrotuzumab
|
| label | Sibrotuzumab
|
| NCI_META_CUI | CL563157
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| code | C156438
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| prefixIRI | NCIT:C156438
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| in_subset | |
| Preferred_Name | Sibrotuzumab
|
| FDA_UNII_Code | 552U6E1NIW
|
| Contributing_Source | FDA
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| Maps_To | Sibrotuzumab
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| CAS_Registry | 216669-97-5
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Immunologic Factor
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| Delete | Subject | Author | Type | Created |
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