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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C156015
http://purl.obolibrary.org/obo/NCIT_C156015
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|---|---|
| Preferred Name | Adenoviral Cancer Vaccine PF-06936308 |
| Definitions |
A cancer vaccine composed of a replication-defective E1-deleted adenovirus vector based on chimpanzee adenovirus serotype 68 (AdC68) expressing three not yet disclosed tumor-associated antigens (TAAs), with potential immunostimulating and antineoplastic activities. Upon vaccination with the adenoviral cancer vaccine PF-06936308, the adenovirus infects cells and expresses the TAAs. In turn, the TAAs activate the immune system to produce a cytotoxic T-lymphocyte (CTL) response against cells expressing the TAAs.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A cancer vaccine composed of a replication-defective E1-deleted adenovirus vector based on chimpanzee adenovirus serotype 68 (AdC68) expressing three not yet disclosed tumor-associated antigens (TAAs), with potential immunostimulating and antineoplastic activities. Upon vaccination with the adenoviral cancer vaccine PF-06936308, the adenovirus infects cells and expresses the TAAs. In turn, the TAAs activate the immune system to produce a cytotoxic T-lymphocyte (CTL) response against cells expressing the TAAs. |
|---|---|
| prefLabel | Adenoviral Cancer Vaccine PF-06936308
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| label | Adenoviral Cancer Vaccine PF-06936308
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| NCI_META_CUI | CL562758
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| PDQ_Closed_Trial_Search_ID | 795350
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| code | C156015
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| prefixIRI | NCIT:C156015
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| in_subset |
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| Display_Name | Adenoviral Cancer Vaccine PF-06936308
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| Preferred_Name | Adenoviral Cancer Vaccine PF-06936308
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| Contributing_Source | CTRP
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| Maps_To | Adenoviral Cancer Vaccine PF-06936308
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| NCI_Drug_Dictionary_ID | 795350
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 795350
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| Semantic_Type | Pharmacologic Substance
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