Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C1554
http://purl.obolibrary.org/obo/NCIT_C1554
Preferred Name

Edrecolomab
Definitions
A murine monoclonal IgG2a antibody to tumor-associated epithelial cell adhesion molecule (EpCAM, or 17-1A) antigen. Edrecolomab attaches to EpCAM, a human cell surface glycoprotein that is found on normal epithelial cells and some tumor cells, such as those of colon and breast carcinomas. Upon binding, this agent recruits the body's immune effector cells, which may exhibit antitumor cytotoxicity. (NCI04)
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A murine monoclonal IgG2a antibody to tumor-associated epithelial cell adhesion molecule (EpCAM, or 17-1A) antigen. Edrecolomab attaches to EpCAM, a human cell surface glycoprotein that is found on normal epithelial cells and some tumor cells, such as those of colon and breast carcinomas. Upon binding, this agent recruits the body's immune effector cells, which may exhibit antitumor cytotoxicity. (NCI04)
prefLabel
Edrecolomab
label
Edrecolomab
PDQ_Closed_Trial_Search_ID
39352
code
C1554
Has_Target
prefixIRI
NCIT:C1554
in_subset
Display_Name
Edrecolomab
Preferred_Name
Edrecolomab
FDA_UNII_Code
0KYI9U9FSJ
Contributing_Source
CTRP
FDA
Maps_To
Edrecolomab
CAS_Registry
156586-89-9
NSC Number
377963
NCI_Drug_Dictionary_ID
39352
Legacy Concept Name
Edrecolomab
type
ALT_DEFINITION
A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
39352
Semantic_Type
Amino Acid, Peptide, or Protein
Pharmacologic Substance
Immunologic Factor
UMLS_CUI
C0279218
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