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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C154558
http://purl.obolibrary.org/obo/NCIT_C154558
|
|---|---|
| Preferred Name | Antibody-drug Conjugate SC-005 |
| Definitions |
An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to a currently undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of SC-005 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an unknown mechanism of action.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to a currently undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of SC-005 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an unknown mechanism of action. |
|---|---|
| label | Antibody-drug Conjugate SC-005
|
| prefLabel | Antibody-drug Conjugate SC-005
|
| in_subset | |
| Preferred_Name | Antibody-drug Conjugate SC-005
|
| Is_Value_For_GDC_Property | |
| Maps_To | Antibody-drug Conjugate SC-005
|
| PDQ_Open_Trial_Search_ID | 794353
|
| FDA_UNII_Code | BT8F8AD6WO
|
| prefixIRI | NCIT:C154558
|
| NCI_Drug_Dictionary_ID | 794353
|
| Contributing_Source | FDA
|
| subClassOf | |
| code | C154558
|
| type | |
| PDQ_Closed_Trial_Search_ID | 794353
|
| Semantic_Type | Pharmacologic Substance
|
| NCI_META_CUI | CL555355
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