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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1489
http://purl.obolibrary.org/obo/NCIT_C1489
|
|---|---|
| Preferred Name | Recombinant Interleukin-13 |
| Definitions |
The recombinant analogue of an endogenous cytokine interleukin 13 with potential antineoplastic activity. Produced by lymphocytes and exhibiting a variety of functions, interleukin-13 (therapeutic) inhibits DNA synthesis and regulates inflammatory and immune responses. In animal models, this agent has been shown to kill tumor cells both directly and indirectly by activating the host immune system at the tumor site. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The recombinant analogue of an endogenous cytokine interleukin 13 with potential antineoplastic activity. Produced by lymphocytes and exhibiting a variety of functions, interleukin-13 (therapeutic) inhibits DNA synthesis and regulates inflammatory and immune responses. In animal models, this agent has been shown to kill tumor cells both directly and indirectly by activating the host immune system at the tumor site. (NCI04) |
|---|---|
| prefLabel | Recombinant Interleukin-13
|
| label | Recombinant Interleukin-13
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| code | C1489
|
| prefixIRI | NCIT:C1489
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| in_subset | |
| Preferred_Name | Recombinant Interleukin-13
|
| Maps_To | Recombinant Interleukin-13
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| CAS_Registry | 148157-34-0
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| Legacy Concept Name | Therapeutic_Interleukin-13
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Is_Related_To_Endogenous_Product | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C1522557
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