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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1458
http://purl.obolibrary.org/obo/NCIT_C1458
|
|---|---|
| Preferred Name | Zorubicin Hydrochloride |
| Definitions |
A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. (NCI04) |
|---|---|
| prefLabel | Zorubicin Hydrochloride
|
| label | Zorubicin Hydrochloride
|
| PDQ_Closed_Trial_Search_ID | 39590
|
| code | C1458
|
| prefixIRI | NCIT:C1458
|
| in_subset | |
| Preferred_Name | Zorubicin Hydrochloride
|
| FDA_UNII_Code | WXM8D9M6DE
|
| Contributing_Source | FDA
|
| Chemical_Formula | C34H35N3O10.ClH
|
| Maps_To | Zorubicin Hydrochloride
|
| CAS_Registry | 36508-71-1
|
| NSC Number | 164011
|
| NCI_Drug_Dictionary_ID | 39590
|
| Legacy Concept Name | Zorubicin
|
| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39590
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
Antibiotic
|
| UMLS_CUI | C0206788
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| Delete | Subject | Author | Type | Created |
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