Biological and Environmental Research Ontology

Last uploaded: December 23, 2022

Id	http://purl.obolibrary.org/obo/NCIT_C1423 http://purl.obolibrary.org/obo/NCIT_C1423
Preferred Name	Perfosfamide
Definitions	The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04)
Type	http://www.w3.org/2002/07/owl#Class

definition	The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04)
prefLabel	Perfosfamide
label	Perfosfamide
CHEBI_ID	CHEBI:196991
PDQ_Closed_Trial_Search_ID	40474
code	C1423
prefixIRI	NCIT:C1423
in_subset	http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 http://purl.obolibrary.org/obo/NCIT_C157711 http://purl.obolibrary.org/obo/NCIT_C157712 See more See less
Preferred_Name	Perfosfamide
FDA_UNII_Code	U880A4FUDA
Contributing_Source	FDA
Chemical_Formula	C7H15Cl2N2O4P
Maps_To	Perfosfamide
CAS_Registry	39800-16-3
NSC Number	181815
NCI_Drug_Dictionary_ID	40474
Legacy Concept Name	Perfosfamide
type	http://www.w3.org/2002/07/owl#Class
Is_Value_For_GDC_Property	http://purl.obolibrary.org/obo/NCIT_C1909
subClassOf	http://purl.obolibrary.org/obo/NCIT_C697
PDQ_Open_Trial_Search_ID	40474
Accepted_Therapeutic_Use_For	Ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia
Semantic_Type	Organic Chemical Pharmacologic Substance
UMLS_CUI	C0163054

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