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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1417
http://purl.obolibrary.org/obo/NCIT_C1417
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|---|---|
| Preferred Name | Goserelin Acetate |
| Definitions |
The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | The acetate salt of a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH). Continuous, prolonged administration of goserelin in males results in inhibition of pituitary gonadotropin secretion, leading to a significant decline in testosterone production; in females, prolonged administration results in a decrease in estradiol production. (NCI04) |
|---|---|
| prefLabel | Goserelin Acetate
|
| label | Goserelin Acetate
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| PDQ_Closed_Trial_Search_ID | 40224
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| code | C1417
|
| Has_Target | |
| prefixIRI | NCIT:C1417
|
| in_subset |
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| Display_Name | Goserelin Acetate
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| Preferred_Name | Goserelin Acetate
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| FDA_UNII_Code | 6YUU2PV0U8
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| Contributing_Source |
CTRP
FDA
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| Chemical_Formula | C59H84N18O14.C2H4O2
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| Maps_To | Goserelin Acetate
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| CAS_Registry | 65807-02-5
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| NSC Number | 606864
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| NCI_Drug_Dictionary_ID | 40224
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| Legacy Concept Name | Goserelin_Acetate
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| Has_Free_Acid_Or_Base_Form | |
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 40224
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| Accepted_Therapeutic_Use_For | Breast Carcinoma; Prostate Carcinoma; Endometriosis
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| UMLS_CUI | C0700476
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