Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1414
http://purl.obolibrary.org/obo/NCIT_C1414
|
|---|---|
| Preferred Name | Trioxifene Mesylate |
| Definitions |
A mesylate salt form of trioxifene, a nonsteroidal selective estrogen receptor modulator (SERM). Trioxifene competitively inhibits the binding of estradiol to estrogen receptor alpha (ER alpha), resulting in ER alpha-mediated gene expression. Clinical development of Trioxifene has not proceeded because of lack of superior results over tamoxifen and side effect profile. (NCI)
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A mesylate salt form of trioxifene, a nonsteroidal selective estrogen receptor modulator (SERM). Trioxifene competitively inhibits the binding of estradiol to estrogen receptor alpha (ER alpha), resulting in ER alpha-mediated gene expression. Clinical development of Trioxifene has not proceeded because of lack of superior results over tamoxifen and side effect profile. (NCI) |
|---|---|
| prefLabel | Trioxifene Mesylate
|
| label | Trioxifene Mesylate
|
| code | C1414
|
| prefixIRI | NCIT:C1414
|
| in_subset | |
| Preferred_Name | Trioxifene Mesylate
|
| FDA_UNII_Code | 63ZD22G88L
|
| Contributing_Source | FDA
|
| Chemical_Formula | C30H31NO3.CH4O3S
|
| CAS_Registry | 68307-81-3
|
| Legacy Concept Name | Trioxifene_Mesylate
|
| Has_Free_Acid_Or_Base_Form | |
| type | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0146868
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |