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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1401
http://purl.obolibrary.org/obo/NCIT_C1401
|
|---|---|
| Preferred Name | Piperazinedione |
| Definitions |
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest. |
|---|---|
| prefLabel | Piperazinedione
|
| label | Piperazinedione
|
| PDQ_Closed_Trial_Search_ID | 39556
|
| code | C1401
|
| prefixIRI | NCIT:C1401
|
| in_subset | |
| Preferred_Name | Piperazinedione
|
| Maps_To | Piperazinedione
|
| CAS_Registry | 41109-80-2
|
| NSC Number | 135758
|
| NCI_Drug_Dictionary_ID | 39556
|
| Legacy Concept Name | Piperazinedione
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 39556
|
| Semantic_Type |
Organic Chemical
Antibiotic
|
| UMLS_CUI | C0888240
|
| Delete | Subject | Author | Type | Created |
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| No notes to display |