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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1389
http://purl.obolibrary.org/obo/NCIT_C1389
|
|---|---|
| Preferred Name | Menogaril |
| Definitions |
A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin. (NCI04) |
|---|---|
| prefLabel | Menogaril
|
| label | Menogaril
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| PDQ_Closed_Trial_Search_ID | 40153
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| code | C1389
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| prefixIRI | NCIT:C1389
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| in_subset | |
| Preferred_Name | Menogaril
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| FDA_UNII_Code | 8JSV4O30HQ
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| Contributing_Source | FDA
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| Chemical_Formula | C28H31NO10
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| Maps_To | Menogaril
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| CAS_Registry | 71628-96-1
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| NSC Number | 269148
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| NCI_Drug_Dictionary_ID | 40153
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| Legacy Concept Name | Menogaril
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 40153
|
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
Antibiotic
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| UMLS_CUI | C0127527
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