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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C138180
http://purl.obolibrary.org/obo/NCIT_C138180
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|---|---|
| Preferred Name | T-cell Receptor-engineered T-cells |
| Definitions |
T-lymphocytes that have been engineered to express a modified antigen-specific T-cell receptor (TCR). In cancer therapy, the TCR-engineered T-cell recognizes a tumor-specific protein fragment complexed with major histocompatibility complex (MHC) molecules on the surface of the tumor cells and kills the tumor cell.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | T-lymphocytes that have been engineered to express a modified antigen-specific T-cell receptor (TCR). In cancer therapy, the TCR-engineered T-cell recognizes a tumor-specific protein fragment complexed with major histocompatibility complex (MHC) molecules on the surface of the tumor cells and kills the tumor cell. |
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| prefLabel | T-cell Receptor-engineered T-cells
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| label | T-cell Receptor-engineered T-cells
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| NCI_META_CUI | CL525717
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| code | C138180
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| prefixIRI | NCIT:C138180
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| in_subset | |
| Display_Name | T-cell Receptor-engineered T-cells
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| Preferred_Name | T-cell Receptor-engineered T-cells
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| Contributing_Source | CTRP
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| type | |
| subClassOf | |
| Semantic_Type | Classification
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