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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C137821
http://purl.obolibrary.org/obo/NCIT_C137821
|
|---|---|
| Preferred Name | Antibody-drug Conjugate MEDI7247 |
| Definitions |
An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against an unnamed tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of MEDI7247 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against an unnamed tumor-associated antigen (TAA) linked to an as of yet undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of MEDI7247 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an as of yet unknown mechanism of action. |
|---|---|
| prefLabel | Antibody-drug Conjugate MEDI7247
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| label | Antibody-drug Conjugate MEDI7247
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| NCI_META_CUI | CL524897
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| PDQ_Closed_Trial_Search_ID | 789996
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| code | C137821
|
| prefixIRI | NCIT:C137821
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| in_subset |
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| Display_Name | Antibody-drug Conjugate MEDI7247
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| Preferred_Name | Antibody-drug Conjugate MEDI7247
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| FDA_UNII_Code | XZ66R08EI3
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Antibody-drug Conjugate MEDI7247
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| NCI_Drug_Dictionary_ID | 789996
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 789996
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| Semantic_Type | Pharmacologic Substance
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