Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Filgrastim-sndz
Synonyms
Definitions

A biosimilar of filgrastim, a recombinant form of the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Filgrastim-sndz specifically binds to and activates G-CSF receptors with the same biological activity and stability as the endogenous cytokine, thereby controlling the production, differentiation, and function of neutrophilic granulocyte progenitors. This may decrease the duration and prevent the incidence of chemotherapy-induced neutropenia (CIN).
ID

http://purl.obolibrary.org/obo/NCIT_C137804
Accepted_Therapeutic_Use_For

Cancer patients receiving myelosuppressive chemotherapy; Congenital, cyclic, idiopathic or febrile neutropenia; Peripheral blood progenitor cell mobilization
code

C137804
Contributing_Source

CTRP
definition

A biosimilar of filgrastim, a recombinant form of the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Filgrastim-sndz specifically binds to and activates G-CSF receptors with the same biological activity and stability as the endogenous cytokine, thereby controlling the production, differentiation, and function of neutrophilic granulocyte progenitors. This may decrease the duration and prevent the incidence of chemotherapy-induced neutropenia (CIN).
Display_Name

Filgrastim-sndz
in_subset

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978
label

Filgrastim-sndz
NCI_META_CUI

CL524901
Preferred_Name

Filgrastim-sndz
prefixIRI

NCIT:C137804
prefLabel

Filgrastim-sndz
Semantic_Type

Amino Acid, Peptide, or Protein

Pharmacologic Substance
subClassOf

http://purl.obolibrary.org/obo/NCIT_C387
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