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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C136807
http://purl.obolibrary.org/obo/NCIT_C136807
|
|---|---|
| Preferred Name | Antibody-drug Conjugate SC-004 |
| Definitions |
An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to a currently undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of SC-004 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an unknown mechanism of action.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to a currently undisclosed cytotoxic agent, with potential antineoplastic activity. Upon intravenous administration, the monoclonal antibody moiety of SC-004 targets and binds to the TAA expressed on tumor cells. Upon binding and internalization, the cytotoxic agent is released and kills the TAA-expressing cancer cells, through an unknown mechanism of action. |
|---|---|
| prefLabel | Antibody-drug Conjugate SC-004
|
| label | Antibody-drug Conjugate SC-004
|
| PDQ_Closed_Trial_Search_ID | 789553
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| code | C136807
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| Has_Target | |
| prefixIRI | NCIT:C136807
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| in_subset |
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| Display_Name | Antibody-drug Conjugate SC-004
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| Preferred_Name | Antibody-drug Conjugate SC-004
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| FDA_UNII_Code | EBA1W201ZY
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Antibody-drug Conjugate SC-004
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| NCI_Drug_Dictionary_ID | 789553
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 789553
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| Semantic_Type | Pharmacologic Substance
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| UMLS_CUI | C0967625
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